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Table 2 Respective comparison of the percentage of surface receptors and cytotoxic granules positive NK cells in healthy controls and three kinds of cancer patients

From: Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer

 

Healthy controls

Pancreatic cancer

Gastric cancer

Colorectal cancer

 

%

%

P

%

P

%

P

NKG2A

1.5 ± 1.0

1.9 ± 1.0

ns U

1.3 ± 1.2

ns U

1.4 ± 1.0

ns U

NKG2D

92.1 ± 2.7

83.4 ± 8.4

< 0.001 T

86.9 ± 2.9

< 0.001 T

84.9 ± 10.0

< 0.01 U

NKp30

71.8 ± 15.3

46.5 ± 20.2

< 0.001 U

36.6 ± 21.3

< 0.001 U

42.6 ± 19.4

< 0.001 U

NKp44

1.8 ± 0.9

2.4 ± 1.7

ns U

1.7 ± 1.4

ns U

0.9 ± 1.3

ns U

NKp46

84.8 ± 5.1

56.4 ± 22.2

< 0.001 U

50.1 ± 29.5

< 0.001 U

55.1 ± 24.0

< 0.001 U

DNAM-1

91.4 ± 4.6

87.2 ± 5.5

< 0.01 U

87.7 ± 7.8

ns U

89.5 ± 5.1

ns U

KIR3DL1

9.6 ± 2.7

19.8 ± 11.4

< 0.001 U

17.9 ± 12.3

< 0.001 U

19.5 ± 13.1

< 0.001 U

Granzyme B

97.9 ± 1.6

96.9 ± 2.4

ns U

97.8 ± 2.0

ns U

97.4 ± 2.5

ns U

Perforin

95.2 ± 3.0

79.9 ± 16.0

< 0.01 U

81.2 ± 15.5

< 0.001 U

76.3 ± 19.1

< 0.001 U

  1. U represented Mann–Whitney U-tests and T represented independent t-tests. Data were expressed as means ± standard deviations (Mean ± SD).