Table 4 Concordance of Cav-1 and pERK expression in matched primary and secondary metastatic tumours
Primary | Metastatic | Concordance | |||||
|---|---|---|---|---|---|---|---|
Biomarker | Cav (-) | Cav (+) | pERK (-) | pERK (+) | Concordant / Total | Kappa | P |
Cav (-) | 3 | 0 |  | 14/16 | 0.67 | P = 0.004 | |
Cav (+) | 2 | 11 | |||||
pERK (-) |  | 1 | 0 | 15/16 | 0.64 | P = 0.006 | |
pERK (+) | 1 | 14 | |||||
| Â | Cav(-) pERK(-) | Cav(+) pERK(-) | Cav(-) pERK(+) | Cav(+) pERK(+) | Â | Â | Â |
Cav(-)/pERK(-) | 0 | 0 | 0 | 0 | 14/16 | 0.74 | P < 0.001 |
Cav(+)/pERK(-) | 0 | 1 | 0 | 0 | |||
Cav(-)/pERK(+) | 0 | 0 | 3 | 0 | |||
Cav(+)/pERK(+) | 1 | 0 | 1 | 10 | |||