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Table 4 Concordance of Cav-1 and pERK expression in matched primary and secondary metastatic tumours

From: Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

Primary Metastatic Concordance
Biomarker Cav (-) Cav (+) pERK (-) pERK (+) Concordant / Total Kappa P
Cav (-) 3 0   14/16 0.67 P = 0.004
Cav (+) 2 11
pERK (-)   1 0 15/16 0.64 P = 0.006
pERK (+) 1 14
  Cav(-) pERK(-) Cav(+) pERK(-) Cav(-) pERK(+) Cav(+) pERK(+)    
Cav(-)/pERK(-) 0 0 0 0 14/16 0.74 P < 0.001
Cav(+)/pERK(-) 0 1 0 0
Cav(-)/pERK(+) 0 0 3 0
Cav(+)/pERK(+) 1 0 1 10