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Table 2 Association of the combined expression of Cav-1 and pERK with conventional histological parameters in RCC

From: Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

 

Cav-1 (n = 165)

p-ERK1/2 (n = 164)

Cav-1/pERK1/2 (n = 158)

 

-

+

-

+

All other Tumours

+/+

Grade 1 & 2

69

47

75

43

93

19

Grade 3 & 4

25

24

29

17

36

10

  

P = 0.390

 

P = 0.951

 

P = 0.091

Tumour size <7 cm

49

29

55

24

64

10

>7 cm

45

42

49

36

65

19

  

P = 0.151

 

P = 0.112

 

P = 0.142

Vascular Invasion (-ve)

66

33

71

30

85

10

(+ve)

28

38

33

30

44

19

  

P = 0.002*

 

P = 0.021*

 

P = 0.002*

Capsular Invasion (-ve)

83

55

90

47

109

22

(+ve)

11

16

14

13

20

7

  

P = 0.063

 

P = 0.172

 

P = 0.267

Tumour Stage 1

44

21

50

17

55

7

Stage 2

31

14

28

15

38

4

Stage 3 & 4

19

36

26

28

36

18

  

P = 0.0001*

 

P = 0.011*

 

P = 0.002*

Non- papillary

76

67

84

58

109

28

Papillary

18

4

20

2

20

1

  

P = 0.011*

 

P = 0.004*

 

P = 0.084

  1. * Indicates that statistical significance achieved to at least P < 0.05 with actual P value indicated in the Table itself.
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Journal of Translational Medicine

ISSN: 1479-5876

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