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Figure 4 | Journal of Translational Medicine

Figure 4

From: Caveolin-1 in renal cell carcinoma promotes tumour cell invasion, and in co-operation with pERK predicts metastases in patients with clinically confined disease

Figure 4

Effect of Cav-1 knockdown on signalling molecules in RCC cell lines. (4A) - Secretion of VEGF-A in RCC cells. Data is expressed as mean ± SD (n = 3) and is representative of two independent experiments; (4B) - Activity of AKT/mTOR and ERK signalling pathways and expression of the cell cycle regulators cyclinD1 and c-myc in RCC cell lines as a function of Cav-1 siRNA-mediated knockdown. Western blot is representative of at least four independent experiments.

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