Factors | Number | Overall survival | Â |
---|---|---|---|
Hazard ratio (95% confidence interval) | P value | ||
Age (≤ 70 yr/> 70 yr) | 347/51 | 1.399 (1.015-1.927) | 0.039 |
Gender (Male/Female) | 268/130 | 0.822 (0.644-1.051) | 0.117 |
Pretherapeutic weight loss (No/Yes) | 150/248 | 1.282 (1.014-1.620) | 0.037 |
The 7th tumor-node-metastasis (TNM) staging (AJCC) (Ia + Ib/IIa + IIb/III/IV) | 5/100/86/207 | 1.339 (1.169-1.534) | < 0.001 |
Degree of differentiation (Poorly differentiated or mucinous adenocarcinoma/Moderate differentiated/Well differentiated) | 224/130/44 | 0.666 (0.540-0.822) | < 0.001 |
Surgery (No/Yes) | 228/170 | 0.522 (0.413-0.660) | < 0.001 |
Surgery (radical surgery R0 resection/radical surgery R1 resection/radical surgery R2 resection or Bypass or stent only or exploration or none) | 54/4/112 | 1.410 (1.151-1.727) | 0.001 |
Chemotherapy (No/Yes) | 219/179 | 0.694 (0.552-0.873) | 0.002 |
Baseline CA199 (Normal/Elevated) | 80/297 | 1.614 (1.208-2.156) | 0.001 |
Body mass index (≤ 25/> 25) | 362/36 | 0.802 (0.533-1.209) | 0.291 |
Smoking (No/Yes) | 270/126 | 1.003 (0.791-1.272) | 0.981 |
Alcohol consumption (No/Yes) | 315/80 | 1.183 (0.901-1.552) | 0.225 |
HBV infection | Â | Â | Â |
HBsAg positive/HBsAg negative | 58/340 | 1.285 (0.943-1.749) | 0.110 |
Non HBV infection/CHB +IC +resolved HBV infection | 217/181 | 1.010 (0.807-1.266) | 0.928 |
Non HBV infection/CHB | 217/17 | 0.776 (0.432-1.394) | 0.394 |
Non HBV infection/IC | 217/41 | 1.538 (1.072-2.208) | 0.019 |
Non HBV infection/RHB | 217/123 | 0.923 (0.714-1.193) | 0.541 |
CHB/IC | 17/41 | 2.060 (1.044-4.064) | 0.037 |
Resolved HBV infection/IC | 123/41 | 1.681 (1.137-2.486) | 0.009 |
Resolved HBV infection/CHB | 123/17 | 0.862 (0.471-1.578) | 0.629 |