Skip to main content

Table 3 Association between prognostic factors, HBV infection and overall survival in a univariate analysis

From: The status of HBV infection influences metastatic pattern and survival in Chinese patients with pancreatic cancer

Factors

Number

Overall survival

 

Hazard ratio (95% confidence interval)

P value

Age (≤ 70 yr/> 70 yr)

347/51

1.399 (1.015-1.927)

0.039

Gender (Male/Female)

268/130

0.822 (0.644-1.051)

0.117

Pretherapeutic weight loss (No/Yes)

150/248

1.282 (1.014-1.620)

0.037

The 7th tumor-node-metastasis (TNM) staging (AJCC) (Ia + Ib/IIa + IIb/III/IV)

5/100/86/207

1.339 (1.169-1.534)

< 0.001

Degree of differentiation (Poorly differentiated or mucinous adenocarcinoma/Moderate differentiated/Well differentiated)

224/130/44

0.666 (0.540-0.822)

< 0.001

Surgery (No/Yes)

228/170

0.522 (0.413-0.660)

< 0.001

Surgery (radical surgery R0 resection/radical surgery R1 resection/radical surgery R2 resection or Bypass or stent only or exploration or none)

54/4/112

1.410 (1.151-1.727)

0.001

Chemotherapy (No/Yes)

219/179

0.694 (0.552-0.873)

0.002

Baseline CA199 (Normal/Elevated)

80/297

1.614 (1.208-2.156)

0.001

Body mass index (≤ 25/> 25)

362/36

0.802 (0.533-1.209)

0.291

Smoking (No/Yes)

270/126

1.003 (0.791-1.272)

0.981

Alcohol consumption (No/Yes)

315/80

1.183 (0.901-1.552)

0.225

HBV infection

   

HBsAg positive/HBsAg negative

58/340

1.285 (0.943-1.749)

0.110

Non HBV infection/CHB +IC +resolved HBV infection

217/181

1.010 (0.807-1.266)

0.928

Non HBV infection/CHB

217/17

0.776 (0.432-1.394)

0.394

Non HBV infection/IC

217/41

1.538 (1.072-2.208)

0.019

Non HBV infection/RHB

217/123

0.923 (0.714-1.193)

0.541

CHB/IC

17/41

2.060 (1.044-4.064)

0.037

Resolved HBV infection/IC

123/41

1.681 (1.137-2.486)

0.009

Resolved HBV infection/CHB

123/17

0.862 (0.471-1.578)

0.629

  1. Hazard ratios and 95% confidence intervals were calculated with the Cox proportional-hazards model. P value was worked out by Kaplan-Meier method with log-rank test.
  2. CHB, chronic HBV infection, IC, inactive carriers.