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Table 4 Baseline clinical profiles and responses after CHP-NY-ESO-1 vaccinations

From: Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients

100 μg

200 μg

pt No.

Response to previous therapies (duration time, weeks)

*sum of tumor diameters (mm)

Tumor response (BOR)

Time-to-progression (weeks)

Survival (weeks)

pt No.

Response to previous therapies (duration time, weeks)

*sum of tumor diameters (mm)

Tumor response (BOR)

Time-to-progression (weeks)

Survival (weeks)

100-01

PR (4)

NA

PD

6

31

200-01

PR (29)

24

SD

17

70

100-02

SD

53

NE

4

6

200-02

NE

25

SD

18

33

100-03

NE

144

NE

4

6

200-03

PR (32)

55

PD

6

37

100-04

PD

182

PD

5

17

200-04

PR (30)

NA

PD

6

50

100-05

CR (38)

101

NE

4

4

200-05

PR (32)

NA

PD

6

72

100-06

SD

69

PD

6

31

200-06

NE

32

SD

18

54

100-07

CR (15)

78

PD

6

29

200-07

NE

205

NE

6

8

100-08

NE

39

SD

18

23

200-08

PR (12)

16

SD

11

33

100-09

SD

18

PD

6

8

200-09

CR (96)

88

PD

6

45

100-10

CR (24)

NA

SD

11

60

200-10

SD

NA

SD

12

48

100-11

SD

31

SD

12

20

200-11

SD

NA

NE

6

12

100-12

PR (9)

NA

NE

16

28

200-12

SD

NA

SD

12

33

100-13

PR (16)

NA

NE

52

59

      
  1. *target lesions determined based on RECIST criteria.