Table 2 Adverse events during CHP-NY-ESO-1 vaccinations
100 μg(n = 13) | 200 μg(n = 12) | Total | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adverse event | Grade | Grade | |||||||||||
1 | 2 | 3 | 4 | 5 | Subtotal | 1 | 2 | 3 | 4 | 5 | Subtotal | ||
Skin reaction | 12 | 0 | 0 | 0 | 0 | 12 | 12 | 0 | 0 | 0 | 0 | 12 | 24 |
Swallowing disturbance | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 0 | 4 | 1 | 0 | 5 | 8 |
Diarrhea | 0 | 0 | 2 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 1 | 3 |
Fever | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
Decreased lymphocytes count | 0 | 0 | 7 | 0 | 0 | 7 | 0 | 0 | 3 | 0 | 0 | 3 | 10 |
Decreased Na level | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 4 |
Decreased Hb level | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 |
Elevated ALT/AST level | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |
Elevated uric acid level | 0 | 0 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 |