Table 3 MS/MS data of salivary proteins found differentially expressed between CFS patient and his healthy twin
n° spot | Protein name | ID | Gene name | MW | pI | Matched peptides | Coverage | Best ion score | Peptide identified | ||
|---|---|---|---|---|---|---|---|---|---|---|---|
obs | th | obs | th | ||||||||
Immune system | |||||||||||
91 | Polymeric immunoglobulin receptor | P01833 | PIGR | 80 | 83 | 5.6 | 5.6 | 7 | 12% | 82.8 | (R)QSSGENcDVVVNTLGKR(A) |
815 | Ig alpha-1 chain C region | P01876 | IGHA1 | 38 | 38 | 6.2 | 6.1 | 2 | 7% | 60.9 | (K)TFTcTAAYPESK(T) |
1509 | Cyclophilin A | P62937 | PPIA | 18 | 18 | 7.5 | 7.7 | 6 | 46% | 63.1 | (K)KITIADcGQLE(-) |
Inflammatory response | |||||||||||
1575 | Cystatin-C | P01034 | CST3 | 16 | 16 | 9.3 | 9 | 3 | 25% | 49.7 | (R)ALDFAVGEYNK(A) |
1620 | Cystatin-B | P04080 | CSTB | 14 | 11 | 6.6 | 7 | 4 | 70% | 51.3 | (K)VHVGDEDFVHLR(V) |
1621 | Protein S100-A7 | P31151 | S100A7 | 14 | 11 | 6 | 6 | 2 | 23% | 25.9 | (R)SIIGmIDmFHK(Y) |
Metabolism | |||||||||||
545 | 6-phosphogluconate dehydrogenase, decarboxylating | P52209 | PGD | 48 | 53 | 6.7 | 6.8 | 2 | 6% | 69.2 | (K)GILFVGSGVSGGEEGAR(Y) |
1736 | Zinc-alpha-2-glycoprotein | P25311 | AZGP1 | 36 | 34 | 5.5 | 5.7 | 8 | 27% | 67.5 | (R)AKAYLEEEcPATLR(K) |
1736A | Zinc-alpha-2-glycoprotein | P25311 | AZGP1 | 36 | 34 | 5.5 | 5.7 | 2 | 5% | 94.3 | (R)AKAYLEEEcPATLR(K) |
Signal transduction | |||||||||||
528 | Rab GDP dissociation inhibitor beta | P50395 | GDI2 | 50 | 51 | 5.9 | 6.1 | 3 | 9% | 50.9 | (R)mTGSEFDFEEmKR(K) |
1038 | 14-3-3 protein sigma | P31947 | SFN | 33 | 28 | 4.6 | 4.7 | 8 | 38% | 84.7 | (K)SNEEGSEEKGPEVR(E) |
1051 | 14-3-3 protein zeta/delta | P63104 | YWHAZ | 33 | 28 | 4.8 | 4.7 | 3 | 20% | 45.5 | (K)LAEQAERYDDmAAcmK(S) |
Others | |||||||||||
452 | Serum albumin | P02768 | ALB | 57 | 69 | 6.2 | 5.9 | 8 | 14% | 84.5 | (K)VPQVSTPTLVEVSR(N) |
501 | Alpha-amylase 1 | P04745 | AMY1A | 52 | 58 | 6.5 | 6.5 | 5 | 11% | 98.3 | (K)TGSGDIENYNDATQVR(D) |