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Table 4 Characterization of PDGCX mouse models

From: The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere

Model ID Her2 amp PTEN analysis PI3KCA mutation
aCGH MLPA IHC Sequencing
SGC020 (-) Exon2-6 deletion (-) Wild-type
SGC100 (-) N/A 70% ++ (C&N) H1047R