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Table 4 Characterization of PDGCX mouse models

From: The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere

Model ID

Her2 amp

PTEN analysis

PI3KCA mutation

aCGH

MLPA

IHC

Sequencing

SGC020

(-)

Exon2-6 deletion

(-)

Wild-type

SGC100

(-)

N/A

70% ++ (C&N)

H1047R