From: The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere
Model ID
Her2 amp
PTEN analysis
PI3KCA mutation
aCGH
MLPA
IHC
Sequencing
SGC020
(-)
Exon2-6 deletion
Wild-type
SGC100
N/A
70% ++ (C&N)
H1047R