CXCR7 immunohistochemistry. Representative immunohistochemical CXCR7 staining of primary lesions of ESCC of the esophagus (A) strongly positive, (B) weakly positive and (C) negative. (D) Primary lesion of a CXCR7-positive EAC, (E) CXCR7-positive lymph node metastasis, (F) CXCR7-negative lymph node metastasis and (G) positive liver metastasis. (H) and (I) Healthy esophageal mucosa. (J) Complete scan of the esophagus TMA.