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Table 2 Oxidative damage and cross-sectional area of myofibers from PAD and control patients

From: Oxidative damage and myofiber degeneration in the gastrocnemius of patients with peripheral arterial disease

 

Controls (n = 21)

PAD (n = 34)

p-value

Carbonyl Content (gsu*) (mean ± SD)

486 ± 135

695 ± 132

< 0.0001

HNE Content (gsu) (mean ± SD)

261 ± 101

436 ± 119

< 0.0001

Cross-Sectional Area ‡ (mean ± SD)

5,324 ± 1,371

3,760 ± 1,546

0.0003

  1. *Grayscale units (12-bit gray scale) of background-corrected fluorescence emission from labeled carbonyl groups and HNE adducts.
  2. ‡Cross-sectional area is given in square microns (μ2).
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Journal of Translational Medicine

ISSN: 1479-5876

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