Cardiac protein levels of PPARα, PPARδ and PPARγ in mice. Representative Western blot (A) exhibited cardiac protein expression (B) of PPARα, PPARδ, and PPARγ in mice. α-tubulin was used as endogenous control. Irb = irbesartan, PPAR, peroxisome proliferator-activated receptor. n = 5 for each group. **P < 0.01 compared with Ace2+/y control group; #, P < 0.05 compared with Ace2-/y control group.