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Figure 1 | Journal of Translational Medicine

Figure 1

From: Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice

Figure 1

Effects of irbesartan on myocardial fibrosis in ACE2KO mice. Representative images of Picrosirius red (A−D) and Masson trichrome (E−H) staining showed myocardial fibrosis and collagen volume fraction (CVF) were attenuated in irbesartan (Irb)-treated Ace2-/y mice than in Ace2-/y control mice (×100 magnification). n = 4 for each group. **P < 0.01 compared with Ace2+/y control group; #, P < 0.05, compared with Ace2-/y control group.

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