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Table 2 Distributions of allele and genotype frequencies of NOS1 SNPs in children with and without endothelial dysfunction

From: Genetic variance in Nitric Oxide Synthase and Endothelin Genes among children with and without Endothelial Dysfunction

SNP Allele Endothelial function Endothelial dysfunction P- value OR CI 95%
n = 84 n = 38
rs6490121 A/G n % n %    
AA 31 37 20 53 0.046 5.26 1.16-23.89
GA 34 40 16 42    
GG 19 23 2 5    
Allele A 96 57 56 74    
Allele G 72 43 20 26    
rs2293052 C/T n % n %    
CC 53 63 16 42 0.016 1.76 0.46-6.71
TC 20 24 19 50    
TT 11 13 3 8    
Allele C 126 75 51 67    
Allele T 42 25 25 33    
rs3825102 A/C n % n %    
AA 11 13 2 5 0.001 2.97 1.33-6.62
AC 22 26 23 61    
CC 51 61 13 34    
Allele A 44 26 27 36    
Allele C 124 74 49 64    
rs4767529 C/G n % n %    
CC 44 52 12 32 0.049 1.28 0.38-4.31
GC 29 35 22 58    
GG 11 13 4 10    
Allele C 117 70 46 61    
Allele G 51 30 30 39    
rs561712 A/G n % n %    
AA 13 15 4 10 0.037 2.34 1.03-5.32
AG 30 36 23 61    
GG 41 49 11 29    
Allele A 56 33 31 41    
Allele G 112 67 45 59    
rs549098 C/T n % n %    
CC 43 51 11 29 0.032 1.21 0.40-3.67
TC 28 33 22 58    
TT 13 16 5 13    
Allele C 114 68 44 58    
Allele T 54 32 32 42    
rs567581 A/G n % n %    
AA 13 16 5 13 0.022 2.70 1.19-6.14
AG 27 32 22 58    
GG 44 52 11 29    
Allele A 53 32 32 42    
Allele G 115 68 44 58    
rs483589 A/G n % n %    
AA 11 13 11 29 0.008 3.58 1.47-8.70
AG 32 38 19 50    
GG 41 49 8 21    
Allele A 54 32 41 54    
Allele G 114 68 35 46    
rs693534 A/G n % n %    
AA 11 13 13 34 0.011 2.67 1.15-6.18
AG 32 38 15 40    
GG 41 49 10 26    
Allele A 54 32 41 54    
Allele G 114 68 35 46    
rs9658255 C/G n % n %    
CC 41 49 10 26 0.029 0.37 0.14-0.95
GC 32 38 17 45    
GG 11 13 11 29    
Allele C 114 68 37 49    
Allele G 54 32 39 51    
rs1879417 C/T n % n %    
CC 14 17 14 37 0.02 2.73 1.07-6.91
CT 38 45 17 45    
TT 32 38 7 18    
Allele C 66 39 45 59    
  Allele T 102 61 31 41