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Table 1 Demographic characteristics and metabolic data in children with and without endothelial dysfunction

From: Genetic variance in Nitric Oxide Synthase and Endothelin Genes among children with and without Endothelial Dysfunction

Variables

Endothelial function

(n = 84)

Endothelial dysfunction

(n = 38)

P-value

Age (years)

7.60 ± 1.22

8.05 ± 1.32

0.14

Gender (% male)

70.2

63.2

0.16

Ethnicity

   

White Caucasian %

77.9

74.3

0.19

African American %

22.1

25.7

0.22

1BMI z-score

0.99 ± 1.26

1.75 ± 0.98

0.0002

2SBP (mmHg)

105.35 ± 10.84

105.31 ± 11.12

0.50

3DBP (mmHg)

62.60 ± 7.57

62.11 ± 7.70

0.40

4Tmax (sec)

27.47 ± 10.65

61.97 ± 16.92

0.0001

5TG (mg/dl)

71.69 ± 36.42

88.97 ± 52.80

0.04

6TC (mg/dl)

160.60 ± 25.99

166.72 ± 27.12

0.13

7HDL-C (mg/dl)

52.77 ± 10.46

49.67 ± 8.66

0.05

8LDL-C (mg/dl)

93.19 ± 22.11

99.22 ± 23.68

0.10

Glucose (mg/dl)

78.72 ± 16.48

80.59 ± 13.63

0.28

Insulin (mg/dl)

6.44 ± 5.34

8.77 ± 6.53

0.05

9HOMA-IR

1.12 ± 1.21

1.27 ± 1.54

0.29

10CRP (mg/dl)

1.24 ± 3.51

1.32 ± 1.76

0.44

  1. 1BMI Z-score (body mass index-z-score; 2SBP (systolic blood pressure); 3DBP (diastolic blood pressure); 4Tmax (time of maximum perfusion); 5TG (Triglycerides); 6TC (total cholesterol); 7HDL-C (high-density lipoprotein)-cholesterol; 8LDL-C (low-density lipoprotein)-cholesterol; 9HOMA-IR (homeostatic model assessment-insulin resistance); and 10CRP (C-reactive protein).