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Table 5 Haplotype distribution of TLR2, TLR4 and TLR9 polymorphisms in patients with TB and controls

From: Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population

Haplotypes*

TB patients

Controls

X 2

Pcorr

(N = 90)

(N = 90)

 

hf

hf

  

TLR2

    

 TTGT

0.349

0.324

0.243

ns

 TCGT

0.349

0.324

0.243

ns

 CTGG

0.046

0.071

1.053

ns

 CCGG

0.046

0.071

1.053

ns

 CTGT

0.054

0.062

0.103

ns

 CCGT

0.054

0.062

0.103

ns

 TTGG

0.051

0.042

0.154

ns

 TCGG

0.051

0.042

0.154

ns

TLR4

    

 TTTA

0.972

0.972

0.0

ns

 TTCA

0.011

0.017

0.203

ns

TLR9

    

 GGA

0.433

0.550

4.901

ns

 GAA

0.522

0.383

7.007

0.02

 GGG

0.033

0.067

2.105

ns

  1. *Haplotypes: TLR2 [rs3804099, rs121917864, rs5743708, rs7656411].
  2. TLR4 [rs12344353, rs5030725, rs5030710, rs4986790].
  3. TLR9 [rs5743842, rs352139, rs5743836].
  4. ns: non significant, hf: haplotype frequency. Statistically significant values are shown in bold.