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Table 5 Haplotype distribution of TLR2, TLR4 and TLR9 polymorphisms in patients with TB and controls

From: Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population

Haplotypes* TB patients Controls X 2 Pcorr
(N = 90) (N = 90)
  hf hf   
TLR2     
 TTGT 0.349 0.324 0.243 ns
 TCGT 0.349 0.324 0.243 ns
 CTGG 0.046 0.071 1.053 ns
 CCGG 0.046 0.071 1.053 ns
 CTGT 0.054 0.062 0.103 ns
 CCGT 0.054 0.062 0.103 ns
 TTGG 0.051 0.042 0.154 ns
 TCGG 0.051 0.042 0.154 ns
TLR4     
 TTTA 0.972 0.972 0.0 ns
 TTCA 0.011 0.017 0.203 ns
TLR9     
 GGA 0.433 0.550 4.901 ns
 GAA 0.522 0.383 7.007 0.02
 GGG 0.033 0.067 2.105 ns
  1. *Haplotypes: TLR2 [rs3804099, rs121917864, rs5743708, rs7656411].
  2. TLR4 [rs12344353, rs5030725, rs5030710, rs4986790].
  3. TLR9 [rs5743842, rs352139, rs5743836].
  4. ns: non significant, hf: haplotype frequency. Statistically significant values are shown in bold.