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Table 2 Summary of the results of cytomorphological classification of CNHCs detected by ScreenCell® filtration in 8 ml of venous blood of patients with benign (n = 10), malignant (n = 30) renal tumors and healthy controls (n = 20)

From: Are morphological criteria sufficient for the identification of circulating tumor cells in renal cancer?

      Number of CNHC / 8 ml
   Clinical data Time point A* Time point B** Time point C*** Time point D****
Patient number Histological diagnosis TNM Grade Venous invasion MF UMF BF MF UMF BF MF UMF BF MF UMF BF
26 angiomyolipoma - - no 0 2 0 0 0 0 0 0 0 0 0 0
33 angiomyolipoma - - no 0 0 0 0 0 0 0 0 0 0 0 0
29 benign cyst - - - 0 0 0 0 10 0 0 0 30 2 0 0
18 cyst. nephroma - - - 51 4 0 2 0 0 0 127 30 30 380 0
3 oncocytoma - - no 0 560 2 0 0 0 0 0 0 0 251 195
4 oncocytoma - - no 0 0 0 0 2 0 0 40 8 0 2 3
6 oncocytoma - - no 0 3 0 0 0 0 2 35 35 0 19 11
14 oncocytoma - - no 0 0 0 0 39 0 37 8 0 21 5 0
17 oncocytoma - - no 2 136 0 0 0 0 1 0 0 2 0 35
38 oncocytoma - - no 0 0 4 0 0 0 0 0 0 0 0 0
1 ccRCC T2aN0M0 2 yes 0 0 0 0 0 0 ND ND ND ND ND ND
2 ccRCC T3aN0M0 2 yes 0 0 0 0 0 3 0 10 0 0 0 0
7 ccRCC T2aN0M0 2 no 0 0 0 0 0 0 0 6 0 ND ND ND
9 ccRCC T1bN0M0 2 no 3 19 5 0 0 0 ND ND ND 0 0 0
10 ccRCC T1N0M0 2 no 16 0 10 0 0 0 0 0 3 0 22 16
11 ccRCC T1N0M0 2 no 0 0 0 2 0 0 ND ND ND 0 0 0
13 ccRCC T3aN0M0 3 yes 0 19 0 0 0 0 22 158 30 ND ND ND
15 ccRCC T1aN0M0 2 no 0 0 0 0 0 0 0 0 0 0 0 0
16 ccRCC T1aN0M0 2 no 62 56 0 0 0 0 0 0 0 0 0 0
19 ccRCC T1aN0M0 1 no 1 0 0 0 0 0 0 0 0 0 3 5
20 ccRCC T3aN0M0 3 yes 13 5 0 0 0 0 20 319 58 ND ND ND
22 ccRCC T1aN0M0 1 no 0 32 0 1 0 0 11 0 0 ND ND ND
23 ccRCC T1aN0M0 1 no 1 0 0 0 1 0 2 0 10 5 12 15
24 ccRCC T1N0M0 1 no ND ND ND 0 0 5 0 1 0 0 0 0
25 ccRCC T1aN0M0 2 no 0 1 0 0 0 0 0 1 20 ND ND ND
28 ccRCC T1bN0M0 1 no 0 0 0 0 645 0 5 5 25 0 36 12
30 ccRCC T1N0M0 3 no 0 0 0 31 227 4 0 0 0 0 67 64
32 ccRCC T1aN0M0 2 no 1 0 0 1 0 0 3 26 15 ND ND ND
34 ccRCC T1aN0M0 2 no 0 0 0 0 26 51 0 18 0 ND ND ND
35 ccRCC T1aN0M0 2 no 0 0 0 0 0 0 ND ND ND 0 20 0
36 ccRCC T1aN0M0 3 no 2 125 3 0 0 0 2 1 7 0 0 0
40 ccRCC T1aN0M0 3 no 0 23 0 0 0 0 0 0 15 0 0 0
41 ccRCC T1aN0M0 3 no 0 0 0 0 0 0 1 0 0 3 74 4
42 ccRCC T1N0M0 1 no 0 0 0 0 0 0 0 22 44 58 124 98
27 pap.RCC T1bN0M0 3 no 0 0 0 0 0 0 0 0 0 1 6 0
8 pap.RCC T1N0M0 2 no ND ND ND 0 0 0 0 0 0 0 0 0
12 pap.RCC T3aN0M0 3 yes 0 0 5 0 0 0 11 0 0 ND ND ND
31 pap.RCC T1aN0M0 2 no 0 0 0 0 0 0 ND ND ND ND ND ND
37 pap.RCC T2aN0M0 2 no 0 0 100 19 79 18 1 0 4 ND ND ND
39 reg RCC T2aN0M0 2 yes 0 0 1 1 0 0 1 0 0 1 0 0
C1 Control - - - 0 0 1 - - - - - - - - -
C2 Control - - - 0 0 0 - - - - - - - - -
C3 Control - - - 0 2 2 - - - - - - - - -
C4 Control - - - 0 83 100 - - - - - - - - -
C5 Control - - - 0 0 0 - - - - - - - - -
C6 Control - - - 0 0 0 - - - - - - - - -
C7 Control - - - 0 0 12 - - - - - - - - -
C8 Control - - - 0 0 0 - - - - - - - - -
C9 Control - - - 0 1 0 - - - - - - - - -
C10 Control - - - 0 0 0 - - - - - - - - -
C11 Control - - - 0 1 1 - - - - - - - - -
C12 Control - - - 0 0 0 - - - - - - - - -
C13 Control - - - 0 1 2 - - - - - - - - -
C14 Control - - - 0 0 0 - - - - - - - - -
C15 Control - - - 0 0 0 - - - - - - - - -
C16 Control - - - 0 27 5 - - - - - - - - -
C17 Control - - - 0 1 7 - - - - - - - - -
C18 Control - - - 0 0 0 - - - - - - - - -
C19 Control - - - 0 0 0 - - - - - - - - -
C20 Control - - - 0 1 0 - - - - - - - - -
  1. * One day before surgery.
  2. ** During surgery, after the removal of the tumor.
  3. *** One day after surgery.
  4. **** Eight days after surgery.
  5. ND Not done (sample not available).