Forkhead box transcription factor 1 expression in gastric cancer: FOXM1 is a poor prognostic factor and mediates resistance to docetaxel

Table 3 Results of univariate and multivariate analysis of 5-year survival by Cox proportional hazard model

Variable		Univariate analysis			Multivariate analysis
Variable	n	OR	95.0% CI	P	OR	95.0% CI	P
Age (≤50 years / >50 years)	19/84	0.738	0.363-1.499	0.4
Gender (F/M)	68/35	0.759	0.440-1.308	0.32
Size of tumor (≤5 cm / >5 cm)	73/30	0.287	0.170-0.483	0.001^**	0.532	0.306-0.925	0.025^*
Depth of tumor invasion (T1-2/T3-4)	40/63	0.209	0.108-0.404	0.002^**	7.798	1.993-14.561	0.009^**
Lymph node metastatis (negative/positive)	40/63	0.179	0.090-0.355	0.002^**	0.457	0.192-1.086	0.076
Degree of differentiation (undifferentiated/differentiated)	75/28	1.041	0.593-1.825	0.889
Venous invasion (negative/positive)	61/42	0.375	0.225-0.628	0.001^**	0.758	0.433-1.326	0.332
Neural invasion (negative/positive)	56/47	0.917	0.553-1.523	0.739
FOXM1 expession (negative/positive)	22/81	2.277	1.081-4.796	0.030^*	6.251	2.699-14.478	0.001^**
TNM staging (I-II/III-IV)	45/58	0.118	0.059-0.237	<0.001^**	0.012	0.001-0.099	<0.001^**
Lauren type (intestinal/diffuse and mixed)	87/16	0.700	0.318-1.541	0.376

ISSN: 1479-5876