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Table 6 ABC score

From: Transplantation of human cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells in autism

ABC item Group Baseline 4w 8w 16w 24w
Irritability CBMNC 16.36 ± 9.61 14.00 ± 8.66 9.50 ± 8.81 10.21 ± 9.58 8.14 ± 8.37
Combination 15.00 ± 7.81 11.22 ± 5.76 9.78 ± 4.32 5.67 ± 3.24 4.22 ± 3.19
Control 9.15 ± 5.58 8.31 ± 5.41 8.46 ± 5.41 8.69 ± 5.56 6.92 ± 4.96
Lethargy/Social withdrawal CBMNC 30.71 ± 6.08 26.86 ± 5.26a 24.07 ± 7.08a 23.86 ± 8.62a 24.14 ± 9.65a
Combination 31.00 ± 6.98 25.78 ± 6.50a 22.67 ± 5.27a 21.11 ± 5.82a *16.00 ± 7.92ab
Control 35.08 ± 4.96 34.31 ± 5.14 33.92 ± 4.73 32.46 ± 5.55 *30.54 ± 5.03
Stereotypic behavior CBMNC 29.43 ± 9.77 *22.43 ± 8.98 *18.86 ± 10.52 *18.00 ± 10.86 *17.07 ± 9.93
Combination 28.33 ± 8.47 20.78 ± 8.81 17.22 ± 7.12 13.22 ± 6.78 *9.33 ± 5.81ab
Control 22.77 ± 6.86 20.85 ± 6.63 21.08 ± 4.82 18.38 ± 5.58 17.31 ± 4.05
Hyperactivity CBMNC 11.86 ± 4.55a 10.07 ± 4.63 7.57 ± 4.83 7.29 ± 5.27 6.86 ± 5.26
Combination 11.89 ± 6.88a 9.33 ± 5.87 7.22 ± 5.19 5.89 ± 3.37 4.67 ± 3.74
Control 6.08 ± 3.15 6.31 ± 2.81 6.46 ± 3.38 6.15 ± 3.39 5.08 ± 2.40
Inappropriate speech CBMNC 5.71 ± 4.30a 3.79 ± 3.29 3.43 ± 3.34 2.93 ± 2.87 2.14 ± 2.32
Combination 5.56 ± 2.83a 4.56 ± 2.92 3.11 ± 1.62 3.22 ± 2.44 2.56 ± 2.19
Control 2.38 ± 2.10 2.69 ± 2.21 3.00 ± 2.27 2.92 ± 2.56 2.46 ± 2.63
Total score CBMNC 94.07 ± 21.98 77.14 ± 22.4 *63.43 ± 29.93 *62.29 ± 33.98 *58.36 ± 31.73a
  Combination 91.78 ± 25.92 71.67 ± 22.57 60.00 ± 18.94 49.11 ± 14.61 *36.78 ± 16.95ab
  Control 75.46 ± 12.05 72.46 ± 12.95 72.92 ± 11.43 68.62 ± 12.58 *62.31 ± 11.3
  1. Note: *Aberrant behavioral scores at different follow-up time-points compared with baseline scores in each group (p < 0.05). aAberrant behavioral scores of the Combination or CBMNC group compared with the Control group (p < 0.05). bComparison of aberrant behavioral scores of the Combination group with the CBMNC group (p < 0.05).