Table 2 Contribution of individual TNF-α and LT-α gene polymorphisms in CF lung disease progression

TNF-α-308GA – LT-α + 252AA

96.9 ± 9.5 (n = 12)

91.5 ± 10.4 (n = 12)

TNF-α-308GG – LT-α + 252AA

78.8 ± 2.6 (n = 94)

0.025

70.3 ± 2.8 (n = 94)

0.015

TNF-α-308GA – LT-α + 252AG

72.5 ± 4.2 (n = 27)

0.008

66.4 ± 5.5 (n = 27)

0.009

TNF-α-308GG – LT-α + 252AG

78.1 ± 3.8 (n = 33)

0.025

72.6 ± 4.6 (n = 32)

0.027

TNF-α-308GG – LT-α + 252GG together with

TNF-α-308GA – LT-α + 252GG

76.1 ± 6.8 (n = 11)

0.029

69.3 ± 8.9 (n = 11)

0.039