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Figure 2 | Journal of Translational Medicine

Figure 2

From: A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effect

Figure 2

An overview of modules detected in DHN. 19 modules were detected in DHN out of which 4 modules represent ca. 97% of the network. (A) The largest module is enriched for regulation of transcription. (B) The second module with 1540 interconnected proteins representing hormone and hormone receptor signaling pathways. (C) The third module with 1420 proteins enriched for GPCR signaling. (D) The fourth module containing 1312 nodes is enriched for protein translation and induction of apoptosis.

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