Figure 4

Gelatin zymography of MMPs activities in aortic tissues. A) Gelatin zymography of 4 representative specimens from positive control (from kit), and Sham, CONT, and MSC4 groups. B-E) Zymographic band densities from all tissue samples were quantified by densitometry. Enzyme activities of (pro- and active-) MMP-2 and MMP-9 were significantly decreased in group MSC4 compared with group CONT. The enzyme activities of MMPs are expressed as a mean ±SEM (n =10-12). *P < 0.05. ***P <0.001 vs. group CONT, assessed by one-way ANOVA. MMPs, matrix metalloproteinases.