Skip to main content

Table 2 Cox regression analysis of clinicopathological features and molecular signatures in GC

From: Metallothionein 2A inhibits NF-κB pathway activation and predicts clinical outcome segregated with TNM stage in gastric cancer patients following radical resection

  Multivariate analysis
Covariate by end point Hazard ratio 95% CI P- value
Age ≥ 60 years 1.300 0.840 to 1.934 0.254
Sex 0.823 0.499 to 1.233 0.292
Differentiation 0.753 0.509 to 1.778 0.875
Tumor invasive depth 1.914 1.389 to 2.638 < 0.001
Lymph node status 1.291 1.034 to 1.612 0.024
Distant metastasis 2.595 1.332 to 5.056 0.005
MT2A 0.429 0.187 to 0.683 0.002
IκB-α 0.779 0.524 to 1.311 0.423
p-IκB-α 1.857 1.256 to 2.912 0.003