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Table 2 Cox regression analysis of clinicopathological features and molecular signatures in GC

From: Metallothionein 2A inhibits NF-κB pathway activation and predicts clinical outcome segregated with TNM stage in gastric cancer patients following radical resection

 

Multivariate analysis

Covariate by end point

Hazard ratio

95% CI

P- value

Age ≥ 60 years

1.300

0.840 to 1.934

0.254

Sex

0.823

0.499 to 1.233

0.292

Differentiation

0.753

0.509 to 1.778

0.875

Tumor invasive depth

1.914

1.389 to 2.638

< 0.001

Lymph node status

1.291

1.034 to 1.612

0.024

Distant metastasis

2.595

1.332 to 5.056

0.005

MT2A

0.429

0.187 to 0.683

0.002

IκB-α

0.779

0.524 to 1.311

0.423

p-IκB-α

1.857

1.256 to 2.912

0.003