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Table 1 Logistic regression analysis of clinicopathological features and prognosis in GC

From: Metallothionein 2A inhibits NF-κB pathway activation and predicts clinical outcome segregated with TNM stage in gastric cancer patients following radical resection

Variates No. of cases (n = 258) Survival time (month)   P-value
Sex     
Male 186 66.4 ± 4.6   
Female 72 54.1 ± 4.8   0.604
Age at diagnosis     
<60 173 65.0 ± 4.9   
≥60 85 59.2 ± 5.6   0.867
TNM stage     
I 34 105.5 ± 7.7 I vs. IV < 0.001
II 57 74.0 ± 5.9 II vs. IV < 0.001
III 115 49.1 ± 3.4 III vs. IV 0.010
IV 52 35.8 ± 4.1   
Tumor depth     
pT1 13 87.2 ± 9.9 pT1 vs. pT4 0.005
pT2 50 89.1 ± 9.1 pT2 vs. pT4 < 0.001
pT3 157 49.1 ± 2.9 pT3 vs. pT4 0.159
pT4 38 40.1 ± 5.3   
Lymph node status     
pN0 78 89.8 ± 6.2 pN0 vs. pN3 0.001
pN1 115 50.5 ± 3.4 pN1 vs. pN3 0.212
pN2 49 46.6 ± 6.0 pN2 vs. pN3 0.326
pN3 16 47.5 ± 12.6   
Distant metastasis     
pM0 232 67.5 ± 4.3   
pM1 26 27.6 ± 5.8   < 0.001
Degree of differentiation     
D1 54 76.0 ± 6.0   
D0 204 59.8 ± 4.4   0.011
MT2A expression     < 0.001
low 202 53.9 ± 3.4
high 56 86.9 ± 9.2
IκB-α expression     
low 164 61.6 ± 4.9   
high 94 64.9 ± 5.1   0.248
p-IκB-α expression     
low 126 74.1 ± 5.3   
high 132 47.7 ± 3.4   0.005
  1. M0: no distant metastasis; M1: distant metastasis;
  2. D1: well/moderately-differentiated GCs; D0: poorly-differentiated GCs.