Combined MT2A and IκB-α expression status as a prognostic indicator in GC. A, IκB-α expression was not benefit for the clinical outcome (P = 0.248). B, The overall survival was better in subgroup with low expression of p-IκB-α (p- IκB-α-) than that in p-IκB-α + subgroup (P = 0.005). C, The expression of p-IκB-α status was benefit for prognostic prediction in the IκB-α + subgroup (n = 94, P = 0.047). D, Combination of MT2A and IκB-α was benefit for prognostic prediction in GC patients. MT2A+/IκB-α + subgroup had the better outcome than other subgroups (P < 0.05, respectively, other subgroups versus MT2A-/IκB-α-). E, In the MT2A-/IκB-α- subgroup, better survival was in the low level of p-IκB-α expression (n =142, P = 0.026). F, Combined MT2A and p-IκB-α expression together, is better for the prognostic prediction (P < 0.01, respectively, other subgroups versus MT2A-/p-IκB-α+).