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Table 3 Univariate and multivariate analyses for clinical outcome in 103 NSCLC patients

From: Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor

Variables

Overall survival

Hazard ratio

 

Univariate

Multivariate

(95% CI)

SEX

0.010*

0.039

2.22 (.90-5.49)

Histology

0.508

-

-

Stage (I + II vs. III +IV)

<0.0001*

0.041

3.97 (1.05-15.02)

pT

<0.0001*

0.042

-

pN

<0.0001*

0.054

-

pM

0.585

-

-

Diameter (≥30 mm vs. <30mm)

0.002*

0.001

6.53 (2.14-19.86)

Ki-67 labeling (≥10% vs. < 10%)

0.010*

0.284

1.76 (0.62-4.98)

17βHSD1 (high vs. low/negative)

0.003*

0.007

2.83 (1.31-6.09)

17βHSD2 (high vs. low/negative)

0.023*

0.286

0.62 (0.26-1.48)

ERα expression

0.599

-

-

ERβ expression

0.570

-

-

Aromatase expression

0.639

-

-

  1. *Data were considered significant in the univariate analyses, and were examined in the multivariate analyses.