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Table 3 Univariate and multivariate analyses for clinical outcome in 103 NSCLC patients

From: Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor

Variables Overall survival Hazard ratio
  Univariate Multivariate (95% CI)
SEX 0.010* 0.039 2.22 (.90-5.49)
Histology 0.508 - -
Stage (I + II vs. III +IV) <0.0001* 0.041 3.97 (1.05-15.02)
pT <0.0001* 0.042 -
pN <0.0001* 0.054 -
pM 0.585 - -
Diameter (≥30 mm vs. <30mm) 0.002* 0.001 6.53 (2.14-19.86)
Ki-67 labeling (≥10% vs. < 10%) 0.010* 0.284 1.76 (0.62-4.98)
17βHSD1 (high vs. low/negative) 0.003* 0.007 2.83 (1.31-6.09)
17βHSD2 (high vs. low/negative) 0.023* 0.286 0.62 (0.26-1.48)
ERα expression 0.599 - -
ERβ expression 0.570 - -
Aromatase expression 0.639 - -
  1. *Data were considered significant in the univariate analyses, and were examined in the multivariate analyses.