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Table 2 Association between clinicopathological variables and 17βHSD1/ 17βHSD2 status in 103 NSCLC patients

From: Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor

103 cases 17βHSD1   17βHSD2
High n=51 Low/Negative n=52 P High n=54 Low/Negative n=49 P
SEX Male 31 31   36 26  
Female 20 21 0.903 18 23 0.158
Histology Adeno 38 39   35 42  
SCC 11 12   16 7  
Adeno squamous 2 1 0.826 3 0 0.031
Stage I 28 40   27 41  
II 7 2   7 2  
III 15 8   18 5  
IV 1 2 0.055 2 1 0.004
pT pT1 20 27   18 29  
pT2 25 20   26 19  
pT3 3 2   4 1  
pT4 3 4 0.617 6 0 0.010
pN pN0 34 44   36 42  
pN1 6 3   7 2  
pN2 11 5 0.100 11 5 0.065
pM pM0 50 49   52 47  
pM1 1 3 0.306 2 2 0.921
Diameter*   15-65 (30) 10-90 (27) 0.156 18-75 (31.5) 10-90 (24) 0.002
Ki-67 %*   0-54.2 (17.6) 0-47.2 (16.6) 0.697 0-54.2 (18.3) 0-47.2 (13.4) 0.127
ERα positive 15 9 0.244 14 10 0.641
negative 37 42   40 39  
ERβ positive 49 43 0.097 50 42 0.257
negative 3 8   4 7  
Aromatase positive 47 39 0.057 47 39 0.309
  negative 5 12   7 10  
  1. Statistical analysis was conducted by Fisher exact test, Wilcoxon rank sum test, and Pearson χ2 test.
  2. * Data were continuous variables and the median with minimum-maximum values were presented.