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Table 2 Association between clinicopathological variables and 17βHSD1/ 17βHSD2 status in 103 NSCLC patients

From: Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor

103 cases

17βHSD1

 

17βHSD2

High n=51

Low/Negative n=52

P

High n=54

Low/Negative n=49

P

SEX

Male

31

31

 

36

26

 

Female

20

21

0.903

18

23

0.158

Histology

Adeno

38

39

 

35

42

 

SCC

11

12

 

16

7

 

Adeno squamous

2

1

0.826

3

0

0.031

Stage

I

28

40

 

27

41

 

II

7

2

 

7

2

 

III

15

8

 

18

5

 

IV

1

2

0.055

2

1

0.004

pT

pT1

20

27

 

18

29

 

pT2

25

20

 

26

19

 

pT3

3

2

 

4

1

 

pT4

3

4

0.617

6

0

0.010

pN

pN0

34

44

 

36

42

 

pN1

6

3

 

7

2

 

pN2

11

5

0.100

11

5

0.065

pM

pM0

50

49

 

52

47

 

pM1

1

3

0.306

2

2

0.921

Diameter*

 

15-65 (30)

10-90 (27)

0.156

18-75 (31.5)

10-90 (24)

0.002

Ki-67 %*

 

0-54.2 (17.6)

0-47.2 (16.6)

0.697

0-54.2 (18.3)

0-47.2 (13.4)

0.127

ERα

positive

15

9

0.244

14

10

0.641

negative

37

42

 

40

39

 

ERβ

positive

49

43

0.097

50

42

0.257

negative

3

8

 

4

7

 

Aromatase

positive

47

39

0.057

47

39

0.309

 

negative

5

12

 

7

10

 
  1. Statistical analysis was conducted by Fisher exact test, Wilcoxon rank sum test, and Pearson χ2 test.
  2. * Data were continuous variables and the median with minimum-maximum values were presented.
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Journal of Translational Medicine

ISSN: 1479-5876

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