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Figure 7 | Journal of Translational Medicine

Figure 7

From: Characterization of humoral responses to soluble trimeric HIV gp140 from a clade A Ugandan field isolate

Figure 7

Neutralization activity of sera from immunized rabbits. (A) Neutralization activity in TZM-bl cells obtained with serial dilutions of IgG (expressed as μg/ml) purified from immunized sera is shown as heatmap for each virus tested. Neutralization activity >50% and <50% is indicated in red and orange, respectively, whereas absence of neutralization activity is indicated in grey. Pre-bleed sera showed a negligible neutralization activity (<10%). (B) Correlation matrix between neutralization activity and peptide binding to envelope gp120 regions. (C) Neutralization activity of TriMab.

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