Figure 5
From: Induction of an EMT-like transformation and MET in vitro
Establishment of the conditioned medium (CM) models. CM of MRC-5 cells induced Bel-7402 cells to undergo an EMT-like transformation, while CM of HL-7702 cells or RF/6A cells did not induce such a transformation at day 14. (A) Bel-7402 cells cultured in CM of MRC-5 cells became elongated. (B) and (C) The invasion and migration ability of Bel-7402 cells cultured in CM of MRC-5 cells was increased (p < 0.05). (D) Bel-7402 cells cultured in CM of MRC-5 cells had more actin-rich protrusions.