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Table 3 Dose escalation of donor lymphocyte infusions (DLI)

From: Immunotherapy with FBTA05 (Bi20), a trifunctional bispecific anti-CD3 x anti-CD20 antibody and donor lymphocyte infusion (DLI) in relapsed or refractory B-cell lymphoma after allogeneic stem cell transplantation: study protocol of an investigator-driven, open-label, non-randomized, uncontrolled, dose-escalating Phase I/II-trial

DLI

Haplo-identical SCT

HLA-identical SCT

d7

5 ×105 /kg CD3+ cells

1 ×106 /kg CD3+ cells

d35

1 ×106 /kg CD3+ cells

5 ×106/kg CD3+ cells

d63

5 ×106 /kg CD3+ cells

1 ×107/kg CD3+ cells

  1. SCT stem cell transplantation, HLA human leukocyte antigen.