Table 1 Presence of regulatory cells (T cells [FOXP3 + , CTLA-4 + ], MDSCs [Monocytic, Granulocytic]) in women with LLABCs
Nature of Regulatory Cells | % in the Circulation of Women with LLABCs* (n = 31) | % in the Circulation of HFDs** (n = 10) | AbN (cells/μl) in the Circulation of Women with LLABCs* (n = 25) | AbN (cells/μl) in the Circulation of HFDs (n = 10) |
|---|---|---|---|---|
T regulatory: % (CD4+ CD25+ CD127- FOXP3+); AbN (CD4+ CD25+) | 1.64 ± 0.36*** (7 fold increase) | 0.24 ± 0.02 | 201.33 ± 13.33 (6 fold increase) | 35.71 ± 2.71 |
T regulatory: % (CD4+ CD25+ CD152+); AbN (CD4+ CD25+ CD152+) | 1.43 ± 0.08 (7 fold increase) | 0.21 ± 0.05 | 17.00 ± 0.90 (2 fold increase; p = 0.002) | 9.75 ± 0.55 |
MDSCs: AbN monocyte-derived (CD11b+ CD14+ HLA DR- CD124+ CD33+) | - | - | 28.67 ± 4.33 (3 fold increase) | 10.20 ± 2.80 |
MDSCs: AbN granulocyte-derived (CD11b+ CD14- CD66b+ CD124+ CD15+) | - | - | 185.13 ± 14.86 (1.5 fold increase; p = 0.025) | 129.00 ± 21.00 |