Skip to main content

Table 1 Study inclusion and exclusion criteria

From: A multi-site feasibility study for personalized medicine in canines with Osteosarcoma

Inclusion criteria Exclusion criteria
Client-owned pet dogs ≥ 1 year of age, any gender and weight. Anticipated poor owner compliance.
Informed owner consent prior to enrollment screening. Pregnant or likely to become pregnant.
Suspected diagnosis of primary appendicular OSA (+/− metastasis) via radiographs and physical exam or confirmed diagnosis based cytology or histopathology of the affected limb. Receiving/have received treatment for cancer including chemotherapy, bisphosphonate therapy, prednisone therapy, radiation therapy or immunotherapy, other than Non-steroidal Anti-inflammatory Drugs (NSAIDS).
Any disease stage. Previously amputated limb as a result of OSA.
Naïve (i.e. de novo) cases. Concurrent malignancy that is non-appendicular OSA.
Planned amputation. Primary cancer originated at an anatomical sites other than appendicular OSA.
  Other serious systemic disorder incompatible with this study.
  Acupuncture treatment less than 2 weeks prior to sample collection day (dogs that have commenced acupuncture > 2 weeks prior to Day 0 can be included but they must stay on their acupuncture treatment during the study period).
  Dogs that are participating in another clinical trial, (subjects are allowed to enroll on a trial after the samples have been collected).
  Quality Control (QC) failure (histopathological or genomic).