Role of MUC20 overexpression as a predictor of recurrence and poor outcome in colorectal cancer

Xiao, Xiuying; Wang, Lisha; Wei, Ping; Chi, Yayun; Li, Dali; Wang, Qifeng; Ni, Shujuan; Tan, Cong; Sheng, Weiqi; Sun, Menghong; Zhou, Xiaoyan; Du, Xiang

doi:10.1186/1479-5876-11-151

Journal of Translational Medicine

Table 1 Part of the differentially up-regulated genes

From: Role of MUC20 overexpression as a predictor of recurrence and poor outcome in colorectal cancer

Probe set ID	Gene symble	Gene name	P value	FDR^a	FC^b
226654_at	MUC12	Mucin 12, cell surface associated	0.001	0.000	2.493
206700_s_at	JARID1D	Jumonji, AT rich interactive domain 1D	0.049	0.012	1.914
204351_at	S100P	S100 calcium binding protein P	0.020	0.005	1.881
231814_at	LOC100130716 /// MUC12	Similar to mucin 11 /// mucin 12, cell surface associated	0.020	0.005	1.799
203815_at	GSTT1	Glutathione S-transferase theta 1	0.045	0.011	1.780
228492_at	LOC100130216 /// USP9Y	Hypothetical protein LOC100130216 /// ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)	0.028	0.007	1.770
204885_s_at	MSLN	Mesothelin	0.038	0.009	1.753
207808_s_at	PROS1	Protein S (alpha)	0.001	0.000	1.707
223646_s_at	CYorf15B	Chromosome Y open reading frame 15B	0.036	0.009	1.690
228232_s_at	VSIG2	V-set and immunoglobulin domain containing 2	0.017	0.003	1.673
205174_s_at	QPCT	Glutaminyl-peptide cyclotransferase	0.033	0.008	1.629
236518_at	KIAA1984	KIAA1984	0.001	0.000	1.614
214774_x_at	TOX3	TOX high mobility group box family member 3	0.025	0.006	1.593
203021_at	SLPI	Secretory leukocyte peptidase inhibitor	0.034	0.008	1.581
215108_x_at	TOX3	TOX high mobility group box family member 3	0.021	0.005	1.578
226622_at	MUC20	Mucin 20, cell surface associated	0.005	0.001	1.577
228821_at	ST6GAL2	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	0.010	0.002	1.565
206624_at	LOC100130216 /// USP9Y	Hypothetical protein LOC100130216 /// ubiquitin specific peptidase 9, Y-linked (fat facets-like, Drosophila)	0.031	0.008	1.565
242414_at	QPRT	Quinolinate phosphoribosyltransferase	0.028	0.007	1.560
204044_at	QPRT	Quinolinate phosphoribosyltransferase	0.045	0.011	1.560
214983_at	TTTY15	Testis-specific transcript, Y-linked 15	0.026	0.007	1.559
216623_x_at	TOX3	TOX high mobility group box family member 3	0.025	0.006	1.555

^a: FDR false diagnosis rate. P value and FDR was calculated by the modified t test using random variance model (RVM-t test). ^b: FC fold change, the ratio of probe signal in patients with poor prognosis and good prognosis.

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ISSN: 1479-5876

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