A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemia

Table 5 Summary of serum Cytokines values at screening, 1 month & 6 month follow-up after BM-MSC implantation

Test	Screening		1 month		6 months		Normal range (pg/ml)
	BM-MSC arm	Placebo	BM-MSC arm	Placebo	BM-MSC arm	Placebo
	N = 10	N = 10	N = 9	N = 10	N = 7	N = 10
	Mean (SD)	Mean (SD)	Mean (SD)	Mean (SD)	Mean (SD)	Mean (SD)
Gamma - Interferon (pg/ml)	24.4(13.35)	23.1(24.07)	37.8 (34.35)	20(24.67)	9.1(6.34)	6.6(3.57)	0.01 - 168
Interleukin - 1 (pg/ml)	22.6(14.73)	22.9(15.31)	33.1(23.59)	22.9(21.73)	26.6(29.28)	10(3.26)	0 - 400
Tumor Necrosis Factor - alpha (pg/ml)	14.2(9.16)	13.8(10.11)	16.6(6.16)	15.7(7.98)	11.4(11.65)	4.4(2.47)	0 – 3.22

ISSN: 1479-5876