TY - JOUR AU - Gupta, Pawan K. AU - Chullikana, Anoop AU - Parakh, Rajiv AU - Desai, Sanjay AU - Das, Anjan AU - Gottipamula, Sanjay AU - Krishnamurthy, Sagar AU - Anthony, Naveen AU - Pherwani, Arun AU - Majumdar, Anish S. PY - 2013 DA - 2013/06/10 TI - A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemia JO - Journal of Translational Medicine SP - 143 VL - 11 IS - 1 AB - Peripheral vascular disease of the lower extremities comprises a clinical spectrum that extends from no symptoms to presentation with critical limb ischemia (CLI). Bone marrow derived Mesenchymal Stem Cells (BM- MSCs) may ameliorate the consequences of CLI due to their combinatorial potential for inducing angiogenesis and immunomodulatory environment in situ. The primary objective was to determine the safety of BM- MSCs in patients with CLI. SN - 1479-5876 UR - https://doi.org/10.1186/1479-5876-11-143 DO - 10.1186/1479-5876-11-143 ID - Gupta2013 ER -