TY - JOUR AU - He, Yinghong AU - Rank, Gerhard AU - Zhang, Miaomiao AU - Ju, Junyi AU - Liu, Ronghua AU - Xu, Zhen AU - Brown, Fiona AU - Cerruti, Loretta AU - Ma, Chi AU - Tan, Renxiang AU - Jane, Stephen M. AU - Zhao, Quan PY - 2013 DA - 2013/01/14 TI - Induction of human fetal hemoglobin expression by adenosine-2’,3’-dialdehyde JO - Journal of Translational Medicine SP - 14 VL - 11 IS - 1 AB - Pharmacologic reactivation of fetal hemoglobin expression is a promising strategy for treatment of sickle cell disease and β-thalassemia. The objective of this study was to investigate the effect of the methyl transferase inhibitor adenosine-2’,3’-dialdehyde (Adox) on induction of human fetal hemoglobin (HbF) in K562 cells and human hematopoietic progenitor cells. SN - 1479-5876 UR - https://doi.org/10.1186/1479-5876-11-14 DO - 10.1186/1479-5876-11-14 ID - He2013 ER -