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Table 1 Patient characteristics

From: Low-dose temozolomide before dendritic-cell vaccination reduces (specifically) CD4+CD25++Foxp3+ regulatory T-cells in advanced melanoma patients

Patient ID

Gender

Age (years)

Site of evaluable disease

M1 classification

Previous treatments

28

M

66

Lymph nodes, lung, liver, pelvis

a

BIOCT

29

F

43

Lymph nodes, lung, liver, skin

c

BIOCT

30

M

69

Lymph nodes, skin, bone

c

BIOCT

31

M

57

Lymph nodes, skin

a

BIOCT

32

M

59

Lymph nodes, lung, liver

c

BIOCT

33

F

44

Liver, skin

c

BIOCT, anti-CTLA4Ab (interrupted after 2 cylces due to grade IV toxicity)

34

F

45

Lung, lymph nodes, soft tissue

b

CT and RT

35.

M

73

Lymph nodes, soft tissue, peritoneum

a

Surgery and RT

36

M

68

Skin, lung

b

BIOCT

37

F

35

Pelvis, lymph nodes,skin, peritoneum, lung

b

CT, anti-CTLA4Ab

38

M

51

Lymph nodes, skin, lung

c

anti-CTLA4Ab, CT

39

M

62

Lymph nodes, skin, adrenal gland

c

Leg Stopflow CT, ECT

40

M

47

Lymph nodes,skin, peritoneum

c

anti-CTLA4Ab, CT, RT

41

F

57

Lymph nodes

a

IFN, antiCD137Ab, CT

42

M

49

Lymph nodes, soft tissue, colon

c

CT

43

M

60

Adrenal gland, soft tissue, lung

c

CT

44

M

57

Lung, liver, lymph nodes, soft tissue

c

CT, IFN

Summary

Male 12

Median

 

M1a:4

 

M1b:3

 

Female 5

57 (range 35–73)

 

M1c:10

 
  1. M Male, F Female, BIOCT Biochemotherapy, CT Chemotherapy, RT Radiotherapy, INF Interferon-alfa, ECT Electrochemotherapy, anti-CTLA4Ab, antibody against CTLA4, antiCD137Ab, antibody against.