| TwHF group | Valsartan group | p |
---|---|---|---|
Male: female | 20:14 | 17:14 | 0.805 |
Age (years) | 51.9 ± 9.8 | 51.0 ± 8.9 | 0.784 |
Duration of DM (months) | 126.9 ± 68.1 | 106.8 ± 57.3 | 0.270 |
Duration of DN (months) | 33.8 ± 30.6 | 26.1 ± 28.4 | 0.277 |
ACEI or ARB treatment before the screening phase (n,%) | 17, 50% | 10, 32.3% | 0.208 |
Systolic blood pressure (mmHg) | 140.6 ± 15.8 | 138.3 ± 17.1 | 0.515 |
Diastolic blood pressure (mmHg) | 81.6 ± 11.9 | 84.4 ± 11.1 | 0.233 |
FBG (mmol/L) | 6.04 ± 1.51 | 6.70 ± 1.62 | 0.092 |
Glycosylated hemoglobin (%) | 6.26 ± 1.15 | 6.68 ± 1.26 | 0.202 |
Serum albumin (g/L) | 33.0 ± 5.66 | 33.07 ± 4.74 | 0.988 |
Total cholesterol (mmol/L) | 6.08 ± 1.96 | 5.92 ± 2.21 | 0.702 |
Triglycerides (mmol/L) | 1.85 ± 0.83 | 2.50 ± 2.10 | 0.111 |
Serum creatinine (mg/dl) | 1.92 ± 0.72 | 1.67 ± 0.62 | 0.117 |
eGFR (ml/min/1.73 m2) | 43.07 ± 21.65 | 47.72 ± 20.34 | 0.377 |
Serum creatinine > 1.5 mg/dl (%) | 70.6% | 54.8% | 0.210 |
Urine protein (g/24 h) | 4.99 ± 2.25 | 4.15 ± 1.29 | 0.097 |