Figure 1From: Role of warm ischemia on innate and adaptive responses in a preclinical renal auto-transplanted porcine modelIntensive ischemic injury induces early pro oxidative milieu. The mRNA expressions of p47phox and gp91phox (a), and protein expression of cytoplasmic Cu/Zn SOD (SOD1, b) were investigated in control, WI, CS and WI + CS groups. Ischemia induces early necrosis and apoptosis. The numbers of necrotic tubular cells (c) and positively cleaved caspase 3 tubular cells (d) per field were counted on ten different tissue sections for each experimental condition in the first week of reperfusion. Shown are mean ± SEM. *p < 0.05 versus control. $ p < 0.05 between groups.Back to article page