Skip to main content
Figure 1 | Journal of Translational Medicine

Figure 1

From: Mild therapeutic hypothermia is superior to controlled normothermia for the maintenance of blood pressure and cerebral oxygenation, prevention of organ damage and suppression of oxidative stress after cardiac arrest in a porcine model

Figure 1

Study protocol. Veno-arterial extracorporeal membrane oxygenation (ECMO) was established and at minimal ECMO flow (0.5 L/min) ventricular fibrillation (V Fib) was induced by rapid ventricular pacing. After 20 min of cardiac arrest, circulation was restored by increasing the ECMO flow to 4.5 L/min (100 mL/kg/min); 90 min of reperfusion followed. After 60 min of reperfusion, up to three defibrillation attempts were performed. Blood samples for the measurement of laboratory parameters (Lab) were taken before and 1 min after arrest and then at 30, 60, and 90 min of reperfusion. Stab, stabilization.

Back to article page