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Table 3 Mean fluorescence intensity of VPAC1, VPAC2 and PAC1

From: VPAC1 receptor expression in peripheral blood mononuclear cells in a human endotoxemia model

Time

Granulocytes

Monocytes

Lymphocytes

A - VPAC1

Baseline

30.5 ± 16.5

19.9 ± 11.7

29.6 ± 11.7

LPS 3 hours

24.3 ± 9.3 *

19.9 ± 20.4

34.1 ± 19.0

LPS 6 hours

21.4 ± 9.9 *

15.3 ± 9 *

32.5 ± 17.3

LPS 24 hours

28.5 ± 16.1

18.2 ± 7.3

31.4 ± 23.7

B - VPAC2

Baseline

19.9 ± 5.7

17.4 ± 7.6

23.5 ± 10.9

LPS 3 hours

17.4 ± 7.5

13.6 ± 6.3 *

20.7 ± 10.8

LPS 6 hours

35.7 ± 86.6 *

16.0 ± 9.2

32.4 ± 41.1

LPS 24 hours

18.3 ± 7.9

19.1 ± 12.7

21.1 ± 8.5 *

C - PAC1

Baseline

17.4 ± 6.2

14.8 ± 5.3

21.6 ± 10.2

LPS 3 hours

16.7 ± 8.6

12.5 ± 10.3

15.7 ± 10.2

LPS 6 hours

21.8 ± 28.1

12.5 ± 9.6 *

17.6 ± 7.2

LPS 24 hours

17.4 ± 6.0

15.4 ± 5.8

15.7 ± 6.2

  1. Mean fluorescence intensity values of VPAC1 (A), VPAC2 (B) and PAC1 (C) in granulocytes, monocytes, and lymphocytes. Values are expressed as mean ± SD (n = 20). Differences from baseline are indicated (*p < 0.005, Wilcoxon matched-pairs test).