| | |
MEMBRANOUS(n, %)
|
CYTOPLASMIC(n, %)
|
NUCLEAR(n, %)
|
|---|
|
Variables
|
Cases
|
Low(102)
|
High(207)
|
p
a
|
Low(176)
|
High(133)
|
p
a
|
Low(170)
|
High(139)
|
p
a
|
|
Gender
| | | | | | | | | | |
|
Male
|
134
|
42(31.3)
|
92(68.7)
|
0.586
|
74(55.2)
|
60(44.8)
|
0.590
|
73(54.5)
|
61(45.5)
|
0.868
|
|
Female
|
175
|
60(34.3)
|
115(65.7)
| |
102(58.3)
|
73(41.7)
| |
97(55.4)
|
78(44.6)
| |
|
Age (years)b
| | | | | | | | | | |
|
<52
|
149
|
59(39.6)
|
90(60.4)
|
0.017
|
85(57.0)
|
64(43.0)
|
0.976
|
77(51.7)
|
72(48.3)
|
0.255
|
|
≥52
|
160
|
43(26.9)
|
117(73.1)
| |
91(56.9)
|
69(43.1)
| |
93(58.1)
|
67(41.9)
| |
|
Histologic subtype
| | | | | | | | | | |
|
Squamous carcinoma
|
142
|
47(33.1)
|
95(66.9)
|
0.976
|
87(61.3)
|
55(38.7)
|
0.158
|
85(59.9)
|
57(40.1)
|
0.115
|
|
Adenocarcinoma
|
167
|
55(32.9)
|
119(67.1)
| |
89(53.3)
|
78(46.7)
| |
85(50.9)
|
82(49.1)
| |
|
Histologicalgrade
| | | | | | | | | | |
|
Grade 1
|
126
|
34(27.0)
|
92(73.0)
|
0.032
|
75(59.5)
|
51(40.5)
|
0.644
|
83(65.9)
|
43(34.1)
|
0.001
|
|
Grade 2
|
112
|
36(32.1)
|
76(67.9)
| |
60(53.6)
|
52(46.4)
| |
59(52.7)
|
53(47.3)
| |
|
Grade 3
|
71
|
32(45.1)
|
39(54.9)
| |
41(57.7)
|
30(42.3)
| |
28(39.4)
|
43(60.6)
| |
|
T classification
| | | | | | | | | | |
|
T1
|
71
|
23(32.4)
|
48(67.6)
|
0.069
|
43(60.6)
|
28(39.4)
|
0.349
|
40(56.3)
|
31(43.7)
|
0.727
|
|
T2
|
58
|
23(39.7)
|
35(60.3)
| |
37(63.8)
|
21(36.2)
| |
32(55.2)
|
26(44.8)
| |
|
T3
|
126
|
39(31.0)
|
87(69.0)
| |
70(55.6)
|
56(44.4)
| |
72(57.1)
|
54(42.9)
| |
|
T4
|
54
|
17(31.5)
|
37(68.5)
| |
26(48.1)
|
28(51.9)
| |
26(48.1)
|
28(51.9)
| |
|
Clinical stage
| | | | | | | | | | |
|
I
|
108
|
35(32.4)
|
73(67.6)
|
0.818
|
62(57.4)
|
46(42.6)
|
0.957
|
56(51.9)
|
52(48.1)
|
0.689
|
|
II
|
81
|
29(35.8)
|
52(64.2)
| |
45(55.6)
|
36(44.4)
| |
45(55.6)
|
36(44.4)
| |
|
III
|
120
|
38(31.7)
|
82(68.3)
| |
69(57.5)
|
51(42.5)
| |
69(57.5)
|
51(42.5)
| |
- a Chi-square test.
- b Patients were divided according to the median values of age.
