Figure 1

PEP-1-CAT restored H/R-induced alteration of H9C2 cell morphology while inhibiting H/R-induced LDH release and MDA production. (A) Effect of PEP-1-CAT on H9c2 cell morphology. Upper panel: cell morphology prior to H/R treatment; lower panel: cell morphology with H/R treatment. (B) PEP-1-CAT reduced LDH levels *P<0.01 vs control (CTL); ^&P<0.05 vs H/R; ^#P<0.01 vs H/R or H/R + CAT (CAT); n = 6. (C) PEP-1-CAT decreased MDA levels. *P<0.01 vs control (CTL);^&P<0.05 vs H/R; ^#P<0.01 vs H/R or H/R + CAT (CAT); n = 6.