HCV Envelope protein 2 sequence comparison of Pakistani isolate and In-silico prediction of conserved epitopes for vaccine development

Table 3 B-cell epitopes with their antigenic score

Position	Epitope	BCPred score	Antigenecity score	Antigen/non-antigen
136	TTDPKGAST	0.999	0.6265	Antigen
278	EDRDRSEQH	0.999	âˆ’0.0020	Non-Antigen
191	GGGGRSTNG	0.996	0.4167	Antigen
4	ITGGTAARG	0.994	2.7513	Antigen
268	NWTRGERCD	0.919	0.7977	Antigen
92	ANITGPSDD	0.9	âˆ’0.3755	Non-Antigen
316	HQNIVDVQY	0.892	1.5115	Antigen
115	VKQPTVCGP	0.891	0.5372	Antigen
303	TPMPALSTG	0.854	0.5271	Antigen
223	GPWLTPQRM	0.843	0.8162	Antigen
126	CFTPSPVVV	0.836	1.0952	Antigen
169	GCTSMNSTG	0.821	0.3500	Non-Antigen
212	HPEATYSRC	0.777	âˆ’0.3926	Non-Antigen
31	INTNGSWHI	0.766	1.0793	Antigen
42	TARNCNESI	0.75	0.2912	Non-Antigen
82	FRQGWGPLT	0.747	1.5574	Antigen
180	KTCGGPPCD	0.725	âˆ’0.6164	Non-Antigen
104	CWHYAPRPC	0.725	0.8901	Antigen
65	KLTGCPQRL	0.723	âˆ’0.4238	Non-Antigen

ISSN: 1479-5876