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Table 3 GABRA3, GABRE and GABBR2 gene expression in NSCLC tissues compare with paired non-cancerous tissues

From: Expression of gamma-aminobutyric acid receptors on neoplastic growth and prediction of prognosis in non-small cell lung cancer

Variable N(%) P value
   GABRA3 GABRE GABBR2
Total 61(100) 0.030* 0.036* 0.005**
Gender
 Male 40(66) 0.040* NS NS
 Female 21(34) NS NS 0.008**
Age
 <60 36(59) NS NS 0.046*
 >60 25(41) NS NS 0.014*
Smoking history
 Yes 23(38) NS NS NS
 No 38(62) NS NS 0.014*
Histotype
 Adenocarcinoma 43(70) NS 0.049* NS
 Squamous cell carcinoma 18(30) NS NS 0.020*
Pathological Grade
 I, II 48(79) NS NS 0.008**
 III 13(21) NS NS NS
Pathological Stage
 I, II 47(77) 0.050* NS 0.008**
 III 9(15) NS NS NS
 IV 5(8) NS NS NS
  1. Pathological grade I: well differentiation, grade II: moderately differentiation, grade III: poorly differentiation. Pathological stage refers to the 7th Edition of TNM Classification of Malignant Tumors form UICC. P-value represents the gene expression of GABA receptor in NSCLC tissues compared with that in paired non-cancerous controls. NS: no significant difference. *P < 0.05, ** P < 0.01.