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Table 3 GABRA3, GABRE and GABBR2 gene expression in NSCLC tissues compare with paired non-cancerous tissues

From: Expression of gamma-aminobutyric acid receptors on neoplastic growth and prediction of prognosis in non-small cell lung cancer

Variable

N(%)

P value

  

GABRA3

GABRE

GABBR2

Total

61(100)

0.030*

0.036*

0.005**

Gender

 Male

40(66)

0.040*

NS

NS

 Female

21(34)

NS

NS

0.008**

Age

 <60

36(59)

NS

NS

0.046*

 >60

25(41)

NS

NS

0.014*

Smoking history

 Yes

23(38)

NS

NS

NS

 No

38(62)

NS

NS

0.014*

Histotype

 Adenocarcinoma

43(70)

NS

0.049*

NS

 Squamous cell carcinoma

18(30)

NS

NS

0.020*

Pathological Grade

 I, II

48(79)

NS

NS

0.008**

 III

13(21)

NS

NS

NS

Pathological Stage

 I, II

47(77)

0.050*

NS

0.008**

 III

9(15)

NS

NS

NS

 IV

5(8)

NS

NS

NS

  1. Pathological grade I: well differentiation, grade II: moderately differentiation, grade III: poorly differentiation. Pathological stage refers to the 7th Edition of TNM Classification of Malignant Tumors form UICC. P-value represents the gene expression of GABA receptor in NSCLC tissues compared with that in paired non-cancerous controls. NS: no significant difference. *P < 0.05, ** P < 0.01.
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Journal of Translational Medicine

ISSN: 1479-5876

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