Table 4 Univariate and multivariate Cox regression analyses of different prognostic variables for NPC patients

Univariate analysis (n = 507)

Hsp70 membranal and cytoplasmic staining

low vs. high

0.540 (0.390-0.747)

<0.001

Hsp70 nucleus staining

low vs. high

1.708 (1.241-2.351)

0.001

Age

<46 vs. > = 46

1.644 (1.202-2.249)

0.002

Sex

male vs. female

0.827 (0.574-1.192)

0.308

T stage

T1 + T2 vs. T3 + T4

3.149 (2.159-4.594)

<0.001

N stage

N0 vs. N1 + N2 + N3

2.474 (1.592-3.846)

<0.001

Recurrence or metastasis

No vs. Yes

548.914 (76.728-3.927E3)

<0.001

Clinical stage

I + II vs. III + IV

6.034 (3.352-10.862)

<0.001

Multivariate analysis (n = 507)

Hsp70 cytoplasmic and membranal staining

low vs. high

0.529 (0.360-0.778)

0.001

Hsp70 nuclear staining

low vs. high

2.601 (1.785-3.789)

6.41E-07

Clinical stage

I + II vs. III + IV

3.641 (1.623-8.170)

0.002