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Table 3 Multivariable regression coefficients of covariates predicting KREC and TREC changes from T0 to T72

From: Effects of combined antiretroviral therapy on B- and T-cell release from production sites in long-term treated HIV-1+ patients

 

T72-T0 log KRECs/mL difference

T72-T0 log TRECs/mL difference

 

coefficient

coefficient

log KRECs/mL at T0

−0.473 [−0.775,−0.172]†

n.i.

log TRECs/mL at T0

n.i.

−0.558 [−0.724,−0.391]‡

Viremia at T0 (log DNAcopies/mL)

n.i.

−0.211 [−0.373,−0.0482]†

CD4/CD8

0.868 [0.155,1.58]†

−0.769 [−1.6,0.057] *

Infection duration before therapy start (years)

−0.111 [−0.16,−0.0629]‡

−0.0648 [−0.118,−0.0121]†

R-squared

0.568

0.820

  1. 95% confidence intervals are in square brackets; n.i.: not included in the model. * p <0.10; † p <0.01; ‡ p <0.001.