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Table 1 Baseline characteristics of HIV-1 + patients

From: Effects of combined antiretroviral therapy on B- and T-cell release from production sites in long-term treated HIV-1+ patients

  Group I Group II p -value*
  T0 T6 T12 T72   
Males 32 (88.9) - - - 17 (77.3) -
Age (years) 39 (35–45) - - - 38 (33–43) -
Risk factors for HIV-1:       
· Heterosexual 20 (55.6) - - - 7 (31.8) -
· Homo/bisexual 10 (27.8) - - - 10 (45.5) -
· IVDU 3 (8.3) - - - 5 (22.7) -
Other/unknown 3 (8.3) - - - 0 (0) -
CD4+ T cells (cells/μL) 258 (139–331) 377 (225–505) 419 (247–570) 688 (407–822) 538 (455–691) <0.0001
CD8+ T cells (cells/μL) 754 (637–1338) 781 (598–990) 753 (561–983) 707 (598–805) 757 (595–1138) -
CD4+/CD8+ T-cell ratio 0.3 (0.2–0.4) 0.5 (0.3–0.7) 0.6 (0.4–0.7) 0.8 (0.6–1.1) 0.7 (0.5–1) <0.0001
HIV-1 RNA (copies/mL) 74533 (21264–196233) < 50 (50–50) < 50 (50–50) < 37 (37–37) 14155 (263–33380) <0.01
  1. For continuous variables the medians (interquartile ranges) are shown, while for categorical variables the number (percentage) is shown.
  2. Group I, HIV-1-infected patients enrolled in the SI.S.THER. study; group II, HIV-1-infected patients naive to antiretroviral therapy.
  3. IVDU indicates Intravenous Drug Users.
  4. *p -value of the comparison between group I at T0 and group II.