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Table 1 Baseline characteristics of HIV-1 + patients

From: Effects of combined antiretroviral therapy on B- and T-cell release from production sites in long-term treated HIV-1+ patients

 

Group I

Group II

p -value*

 

T0

T6

T12

T72

  

Males

32 (88.9)

-

-

-

17 (77.3)

-

Age (years)

39 (35–45)

-

-

-

38 (33–43)

-

Risk factors for HIV-1:

      

· Heterosexual

20 (55.6)

-

-

-

7 (31.8)

-

· Homo/bisexual

10 (27.8)

-

-

-

10 (45.5)

-

· IVDU

3 (8.3)

-

-

-

5 (22.7)

-

Other/unknown

3 (8.3)

-

-

-

0 (0)

-

CD4+ T cells (cells/μL)

258 (139–331)

377 (225–505)

419 (247–570)

688 (407–822)

538 (455–691)

<0.0001

CD8+ T cells (cells/μL)

754 (637–1338)

781 (598–990)

753 (561–983)

707 (598–805)

757 (595–1138)

-

CD4+/CD8+ T-cell ratio

0.3 (0.2–0.4)

0.5 (0.3–0.7)

0.6 (0.4–0.7)

0.8 (0.6–1.1)

0.7 (0.5–1)

<0.0001

HIV-1 RNA (copies/mL)

74533 (21264–196233)

< 50 (50–50)

< 50 (50–50)

< 37 (37–37)

14155 (263–33380)

<0.01

  1. For continuous variables the medians (interquartile ranges) are shown, while for categorical variables the number (percentage) is shown.
  2. Group I, HIV-1-infected patients enrolled in the SI.S.THER. study; group II, HIV-1-infected patients naive to antiretroviral therapy.
  3. IVDU indicates Intravenous Drug Users.
  4. *p -value of the comparison between group I at T0 and group II.
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Journal of Translational Medicine

ISSN: 1479-5876

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