Table 2 Response to FTM treatment according to time of TMZ failure for the entire population
Variable | B0 | B1 | B2 | B3 | All |
|---|---|---|---|---|---|
Number of pts | 20 | 50 | 45 | 48 | 163 |
Response to FTM % (N) | |||||
CR | 0 | 2 (1) | 2.2 (1) | 2.1 (1) | 1.8 (3) |
PR | 15 (3) | 10 (5) | 15.6 (7) | 16.7 (8) | 14.1 (23) |
SD | 30 (6) | 24 (12) | 24.4 (11) | 47.9 (23) | 31.9 (52) |
DP | 55 (11) | 64 (32) | 57.8 (26) | 33.3 (16) | 52.1 (85) |
Disease Control % (N) | |||||
Yes | 45 (9) | 36 (18) | 42.2(19) | 66.7 (32) | 47.8 (78) |
PFS-6 m % (N) | |||||
Yes | 25 (5) | 28 (14) | 31.1 (14) | 43.8 (21) | 33.1 (54) |
OS-1y % (N) | |||||
Yes | 25 (5) | 24 (12) | 28.9 (13) | 31.3 (15) | 27.6 (45) |
Time to DP after FTM | |||||
Days median (range) | 111 (83 - 182) | 91 (43 - 156) | 104 (58 - 190) | 139 (62 - 252) | 104 (58 - 193) |