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Table 1 Baseline Characteristics and Flow Cytometry for EPCs

From: Impact of obesity control on circulating level of endothelial progenitor cells and angiogenesis in response to ischemic stimulation

Variables

Control (n = 9)

Obesity (n = 9)

Obesity-C (n = 9)

P* value

Initial body weight (g)

26.3 ± 0.70

25.2 ± 0.61

25.2 ± 0.66

0.655

Final body weight (g)

34.9 ± 1.42a

43.7 ± 1.50b

35.6 ± 2.19a

<0.0001

Final abdominal fat weight (g)

1.59 ± 0.45a

4.14 ± 0.69b

2.37 ± 0.14c

<0.0001

Final total cholesterol (mg/dl)

138.1 ± 10.2a

231.2 ± 7.59b

189.8 ± 7.55c

<0.001

Initial blood glucose (mg/dl)†

98.8 ± 9.4

102 ± 8.2

100.3 ± 8.6

0.667

Final blood glucose (mg/dl)†

144.2 ± 17.4a

306.9 ± 71.4b

182.2 ± 18.8c

<0.0001

C-kit/CD31 (%)

    

Baseline

1.06 ± 0.40

1.15 ± 0.21

1.21 ± 0.37

0.555

18 hour after CLI procedure

1.20 ± 0.44a

2.60 ± 0.49b

4.11 ± 0.98c

<0.0001

Day 14 after CLI procedure

1.02 ± 1.01a

0.75 ± 0.23a

2.40 ± 0.82b

0.0019

Sca-1/KDR (%)

    

Baseline

0.66 ± 0.21

0.85 ± 0.27

0.73 ± 0.39

0.461

18 hour after CLI procedure

0.87 ± 0.25a

1.15 ± 0.24a

1.88 ± 0.16b

0.006

Day 14 after CLI procedure

0.56 ± 0.29

0.38 ± 0.20

0.89 ± 0.56

0.124

CXCR4/CD34 (%)

    

Baseline

0.43 ± 0.27

0.38 ± 0.17

0.56 ± 0.45

0.789

18 hour after CLI procedure

0.54 ± 0.34a

0.68 ± 0.31a

1.34 ± 0.34b

0.006

Day 14 after CLI procedure

0.63 ± 0.69

0.37 ± 0.19

0.79 ± 0.70

0.764

  1. *: by one-way ANOVA on log transformed data.
  2. Different letters (a, b, c) associated with different groups indicate significant difference (at 0.05 level) by Tukey multiple comparison procedure.
  3. † value was observed after 12 fasting in the mice.
  4. C = control; CLI = critical limb ischemia.